Incidence of Second Primary Lung Cancer in Patients with a History of Head and Neck Cancer

Principal Investigator

Name
John Cramer

Degrees
M.D.

Institution
Karmanos Cancer Institute

Position Title
Assistant Professor

Email
jdcramer@med.wayne.edu

About this CDAS Project

Study
NLST (Learn more about this study)

Project ID
NLST-714

Initial CDAS Request Approval
Oct 8, 2020

Title
Incidence of Second Primary Lung Cancer in Patients with a History of Head and Neck Cancer

Summary
Patients with a history of head and neck squamous cell carcinoma (HNSCC) are thought to be at an especially high risk of lung cancer.
However there are a paucity of data on HNSCC patients comparing survival with or without low-dose helical computed tomography (LDCT) screening for lung cancer. Our goal is to compare the incidence of second primary lung cancers (SPLCs) in patients with a history of HNSCC with LDCT or chest X-ray screening for lung cancer.

Aims

1. Determine the incidence of second primary lung cancer in patients with a history of head and neck cancer with LDCT or chest X-ray screening for lung cancer.

Collaborators

None

Related Publications

• Modeling oral cancer screening in the United States population.
  Cramer JD, Grauer J
  Oral Oncol. 2022 Jan; Volume 124: Pages 105656 PUBMED
• Incidence of Head and Neck Cancer With Lung Cancer Screening: Secondary Analysis of a Randomized Controlled Trial.
  Jassal JS, Grauer JS, Cramer JD
  Laryngoscope. 2022 Jan 5 PUBMED
• Incidence of Second Primary Lung Cancer After Low-Dose Computed Tomography vs Chest Radiography Screening in Survivors of Head and Neck Cancer: A Secondary Analysis of a Randomized Clinical Trial.
  Cramer JD, Grauer J, Sukari A, Nagasaka M
  JAMA Otolaryngol Head Neck Surg. 2021 Oct 28 PUBMED