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Principal Investigator
Name
Srinath Somasundaram
Degrees
-
Institution
The Schmahl Science Workshops
Position Title
Student
Email
About this CDAS Project
Study
NLST (Learn more about this study)
Project ID
NLST-442
Initial CDAS Request Approval
Sep 10, 2018
Title
Experimentally Testing the Efficacy of Convolutional Neural Networks and Other Machine Learning Techniques on Staging of Lung Cancer CTs
Summary
According to the American Cancer Association, there have been 234,030 new cases of lung cancer so far this year and is the most common cancer among men and women. A CAD (Computer Aided Design) oriented approach to diagnosis and more specifically the staging, of lung cancer in CT scans, which are the most commonly used modality for diagnosis and initial staging, is important to create a broadly standard and reliable option for diagnosis. A computer-aided design that can identify key nodule and staging details such as size and density through a single scan of the lungs would aid doctors and limit the amount of time and individual attention needed during the diagnosis process ultimately also limiting the use of invasive procedures for staging. While the surface level diagnosis of lung cancer through the use of computer vision has been widely researched, there is little effort focused on the next step of the process, staging. For this, we propose using convolutional neural networks, a machine learning technique used to simulate the mammalian visual cortex, to efficiently stage lung cancer. Convolutional networks have been mainly developed and used for object recognition especially as of late. Thus, our goal is to create and optimize a supervised convolutional neural network through the use of machine learning libraries such as keras and tensorflow, to accurately diagnose and stage lung cancer comparing our approach to others surveyed in literature.
Aims

- Create a pipeline to diagnose and stage lung cancer through ct scans
- Create a convolutional neural network using keras and tensorflow that recognizes tumors and diagnoses through this recognition
- Refine the network to be able to have deeper levels of understanding of the nodule, using this to accurately stage the lung cancer
- Compare the network's capabilities to other approaches in terms of diagnosis and to real life doctors in terms of both diagnosis and staging

Collaborators

Andy Lee of The Harker School