Outcomes of Lung Cancer CT Screening in Clinical Practice Compared to the National Lung Screening Trial

Principal Investigator

Name
David Gierada

Degrees
MD

Institution
Washington University

Position Title
Profess

Email
gieradad@mir.wustl.edu

About this CDAS Project

Study
NLST (Learn more about this study)

Project ID
NLST-426

Initial CDAS Request Approval
Jul 12, 2018

Title
Outcomes of Lung Cancer CT Screening in Clinical Practice Compared to the National Lung Screening Trial

Summary
Clinical practice guidelines for performing lung cancer screening with low dose CT are based on methods used in the National Lung Screening Trial (NLST). However, little is known about the performance of lung cancer screening in the clinical practice setting relative to the NLST. As one of the screening centers in the NLST, we are able to assess how screening under current clinical guidelines compares to screening under NLST guidelines at the same institution. Determining how well intermediate outcomes of screening in clinical practice compare to those found in the NLST may provide an indication of how well lung cancer screening performs in the clinical setting.

Aims

To compare patient characteristics and intermediate outcomes in the Siteman Cancer Center lung cancer screening program with those found in NLST participants who were screened at Washington University.

Collaborators

Chara Rydzak, MD, PhD, Washington University