Comparing Baseline Characteristics and Outcomes of a Minority-Based Lung Cancer Screening Program to the National Lung Screening Trial

Principal Investigator

Name
Mary Pasquinelli

Degrees
MS, FNP-BC, RN, BA

Institution
University of Illinois Hospital and Health Sciences System

Position Title
Director, Lung Cancer Screening Program

Email
mpasqu3@uic.edu

About this CDAS Project

Study
NLST (Learn more about this study)

Project ID
NLST-391

Initial CDAS Request Approval
Feb 13, 2018

Title
Comparing Baseline Characteristics and Outcomes of a Minority-Based Lung Cancer Screening Program to the National Lung Screening Trial

Summary
The National Lung Screening Trial (NLST) showed a 20% reduction in lung cancer (LC) mortality with low-dose computed tomography (LDCT) scanning versus chest radiography for individuals that are at high risk for LC based primarily on age and smoking history. The majority (91%) of the NLST participants were Caucasian and only 4.5% were African American. Yet African Americans have the highest mortality rate from LC compared to other races/ethnicities in the United States and the magnitude of this disparity has actually increased over the past 4 decades. Screening programs tailored to high-risk minority patients could help to reduce this health disparity and save even more lives. The goal of this study is to assess the demographic characteristics and outcomes from an inner-city minority-based population at the University of Illinois at Chicago (UIC) comparted to the NLST.

Aims

Aim 1: To compared baseline demographic characteristics of UIC's minority-based LDCT population to the NLST.

Aim 2: To compare lung cancer screening outcomes of UIC's minority-based LDCT population to the NLST.

Collaborators

Mary M. Pasquinelli, MS, FNP-BC, Department of Medicine, University of Illinois at Chicago
Kevin L. Kovitz, MD, MBA, Division of Pulmonary, Critical Care, Sleep and Allergy Medicine, University of Illinois at
Chicago
Matthew Koshy MD, Department of Radiation Oncology, University of Illinois at Chicago
Martha G. Menchaca, MD, Department of Radiology, University of Illinois at Chicago
Li Liu, PhD, School of Public Health, Division of Epidemiology and Biostatistics, University of Illinois at Chicago
Robert Winn, MD, University of Illinois Cancer Center, University of Illinois at Chicago
Lawrence E. Feldman, MD, Division of Hematology/Oncology, University of Illinois at Chicago