A simulation modeling study examining the downstream effects of follow-up schedules for screen-detected nodules

Principal Investigator

Name
Chung Yin (Joey) Kong

Degrees
Ph.D.

Institution
Massachusetts General Hospital / Harvard Medical School

Position Title
Senior Scientist / Assistant Professor of Radiology

Email
joey@mgh-ita.org

About this CDAS Project

Study
NLST (Learn more about this study)

Project ID
NLST-357

Initial CDAS Request Approval
Sep 28, 2017

Title
A simulation modeling study examining the downstream effects of follow-up schedules for screen-detected nodules

Summary
We will use a microsimulation model to investigate the effectiveness of the Lung-RADS guidelines for management of lung nodules detected by LDCT scans.

Aims

- Determine whether the Lung-RADS guidelines are optimal for follow-up and treatment of lung nodules
- Investigate modifications to Lung-RADS with the aim of improving effectiveness
- Examine the cost-effectiveness of Lung-RADS and other such sets of guidelines
- Formulate recommendations for lung nodule management

Collaborators

Mark Hammer, M.D. (Brigham and Women's Hospital)
Eduardo Barbosa Jr., M.D. (U. Penn Perelman School of Medicine)

Related Publications

• Cost-Effectiveness of Follow-Up for Subsolid Pulmonary Nodules in High-Risk Patients.
  Hammer MM, Palazzo LL, Paquette A, Eckel AL, Jacobson FL, Barbosa EM, Kong CY
  J Thorac Oncol. 2020 Mar 11 PUBMED
• Cancer Risk in Subsolid Nodules in the National Lung Screening Trial.
  Hammer MM, Palazzo LL, Kong CY, Hunsaker AR
  Radiology. 2019 Nov; Volume 293 (Issue 2): Pages 441-448 PUBMED