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Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at OPM.gov.

Approved PLCO Projects

Here you can browse the complete list of projects for PLCO whose requests for data/biospecimens were approved.

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1-20 of 1488
Name Principal Investigator Institution Study Date Approved Project ID
Epstein-Barr virus-associated neo-antigens in advanced prostate cancer Denong Wang SRI International PLCO Feb 2, 2026 2025-0062
Impact of a secondary biomarker on time-to-event risk prediction of prostate cancer mortality in a screening cohort Kristian Stensland The University of Michigan PLCO Jan 26, 2026 PLCO-2012
Association between microplastic concentration in whole blood and risk of colorectal cancer in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial Rena Jones National Cancer Institute PLCO Jan 26, 2026 2025-0059
Incidence Rates of Lung and Bladder Cancer According to Smoking Status and Tumor Subtype: An Analysis of Absolute Risk in Never Smokers Sarina Murray National Cancer Institute PLCO Jan 16, 2026 PLCO-2017
Causal predictive modeling of survival of Breast cancer: A comparative study with machine learning, traditional survival modeling methods along and causal survival models Malinda Iluppangama Loyola University Maryland PLCO Jan 8, 2026 PLCO-2009
Learning about the effectiveness of lung cancer screening in real-world target populations Sarah Robertson Dartmouth College PLCO Dec 22, 2025 PLCO-2005
Evaluating Multi-trait PRS Methods on Cancer Phenotypes in PLCO Phillip Kraft National Cancer Institute PLCO Dec 16, 2025 PLCO-2004
Developing Contextualized Cancer Risk Models: Integrating Polygenic Risk Scores with Environmental, Geospatial, and Social Determinants of Health Data Phillip Kraft National Cancer Institute PLCO Dec 16, 2025 PLCO-2003
Comparative Analysis of Military Veteran Cancer Biomarkers Using the PLCO Dataset as a Civilian Control Cohort Chelsey Simoni HunterSeven Foundation PLCO Dec 10, 2025 PLCO-1989
Identifying Proteomics Associated with Diet Steven Moore National Cancer Institute PLCO Dec 1, 2025 PLCO-2001
Geographical Variation in Estrogen Levels Steven Moore National Cancer Institute PLCO Dec 1, 2025 PLCO-1999
Can we predict early biochemical response after chemotherapy in Stage IV colon cancer patients using baseline clinical and treatment features Dr. Johnson P. Thomas Oklahoma State University PLCO Nov 24, 2025 PLCO-1994
Synthetic Clinical Trial based on Polygenic Risk Scores Mitchell Machiela National Cancer Institute PLCO Nov 24, 2025 PLCO-1998
Building Digital Twin Framework for Personalization of Prostate Cancer Management in Kidney Transplant Patients Naoru Koizumi George Mason University PLCO Nov 17, 2025 PLCO-1997
Competing risks analysis of multiple cancers with application to vitamin D in PLCO Yei Eun Shin Seoul National University PLCO Nov 17, 2025 PLCO-1979
Phytoestrogen Intake and Risk of Endometrial Cancer Michael Reger University of Notre Dame PLCO Nov 13, 2025 PLCO-1996
Investigating Thymic Function in Human Papillomavirus (HPV)-Related Cancer Risk and Survival Eric Engels National Cancer Institute, National Institutes of Health PLCO Sep 29, 2025 PLCO-1991
Predictive analytics with machine learning for ovarian cancer Jacob Levman St. Francis Xavier University PLCO Sep 22, 2025 PLCO-1990
Genetic Associations Between High-Risk Pulmonary Nodules and Risk of Lung Adenocarcinoma and Squamous Cell Carcinoma Douglas Easton University of Cambridge PLCO Sep 22, 2025 PLCO-1987
Development and Validation of Cancer Risk Prediction Models Using Publicly Available Cohort Data Luke Stetson PreOncology PLCO Sep 22, 2025 PLCO-1986