Specific aims of the proposal are (i) to introduce a new model for the changes of biomarker over time which will generalize the available models, (ii) to use the new model to predict the probability of having ovarian cancer, and (iii) to apply the new model to ovarian cancer as well as prostate cancer in PLCO trial.
Longitudinal evaluation of CA-125 velocity and prediction of ovarian cancer.
Xu JL, Commins J, Partridge E, Riley TL, Prorok PC, Johnson CC, Buys SS
Gynecol. Oncol. 2012 Apr; Volume 125 (Issue 1): Pages 70-4 PUBMED