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Principal Investigator
Name
Keyvan Faharani
Degrees
Ph.D.
Institution
CIP, NCI
Position Title
Program Director
Email
About this CDAS Project
Study
NLST (Learn more about this study)
Project ID
NLST-390
Initial CDAS Request Approval
Feb 12, 2018
Title
Lung Interval Challenge
Summary
This project goal is organize a community wide challenge intends to advance methods development on the current clinical impediment to assess nodules status for lung cancer screening subjects with consecutive scans.
We propose to organize though IEEE ISBI 2018 conference, where the participants are required to develop algorithms or re-package computational methods with potential clinical utility to identify malignancy. We will provide sequential low-dose CT (LDCT) scans at two screening intervals from the National Lung Screening Trial (NLST), with matched identified nodules from the same subject. We would like the participating teams to provide estimated nodules dimensions (longest diameter, volume) in the screening interval and the probability of malignancy. The teams are open to use any radiomic descriptors for nodules across time points and or change in size measurements including doubling time (DT) toward their assessment.
Aims

1) Organize Community wide Challenge through IEEE ISBI using diagnostic lung scan with a matched prior baseline scan.
2) Promote the discovery of imaging based biomarker to predict lung cancer status given CT scans.
3) Disseminate findings of the participants in scholarly publication that promotes the use of quantitative image based biomarkers.

Collaborators

Organizing Team
• *Yoganand Balagurunathan, PhD, H.L.Moffitt Cancer Center (MCC), Tampa, FL
• *Keyvan Farahani, PhD, National Cancer Institute, Bethesda, MD
• Dmitry Goldgof, PhD, University of South Florida (USF)Tampa, FL
• Lubomir Hadjiyski, PhD, University of Michigan, Ann Arbor, MI
• Jayashree Kalpathy-Cramer, PhD, Massachusetts General Hospital (MGH), Cambridge, MA
• Michael McNitt-Gray, PhD, University of California, Los Angeles, LA, CA
• Sandy Napel, PhD, Stanford University, Palo Alto, CA
• Data Quality:
Ying Liu, MD, Tianjin Medical University Cancer Institute and Hospital
Qian Li MD, Tianjin Medical University Cancer Institute and Hospital
Matthew Schabath, PhD, H.L.Moffitt Cancer Center (MCC), Tampa, FL
Dr. Robert Gillies, H.L.Moffitt Cancer Center (MCC), Tampa, FL
Dr. Pinsky, National Cancer Center.

*Lead Organizers

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