Skip to Main Content
An official website of the United States government

PLCO Publications

Browse the complete list of publications for PLCO.

Filter results of publications table below

Publication Year
Publications
Title PubMed Authors Journal Year Studies
Pre-diagnostic circulating bile acid concentrations and liver cancer risk: a nested case-control analysis of 12 cohorts. 40972035 Watling CZ, Petrick JL, Graubard BI, Zhang X, Barnett MJ, Buring JE, Chen Y, Eliassen AH, Gaziano JM, Hofmann JN, Huang WY, Kang JH, Koshiol J, Loftfield E, Lee IM, Moore SC, Mucci LA, Neuhouser ML, Newton CC, Palmer JR, Purdue MP, Rosenberg L, Sess… JNCI Cancer Spectr 2025 PLCO
Using Mendelian randomization to investigate etiologic heterogeneity across renal cell carcinoma subtypes. 41170685 Winter TD, Jahagirdar O, Renal Cancer Genetics Consortium, , Johansson M, Brennan P, Machiela MJ, Chanock SJ, Purdue MP, Dutta D Int J Epidemiol 2025 PLCO
Polygenic prediction of body mass index and obesity through the life course and across ancestries. 40691366 Smit RAJ, Wade KH, Hui Q, Arias JD, Yin X, Christiansen MR, Yengo L, Preuss MH, Nakabuye M, Rocheleau G, Graham SE, Buchanan VL, Chittoor G, Graff M, Guindo-Martínez M, Lu Y, Marouli E, Sakaue S, Spracklen CN, Vedantam S, Wilson EP, Chen SH, Ferreir… Nat Med 2025 PLCO
SMARCAL1 is a new osteosarcoma predisposition gene. 40996338 Rafati M, Guenther LM, Egolf LE, Gianferante DM, Kim J, Wang K, Zhu B, Spector LG, Anderson N, Janeway KA, Barkauskas DA, Hawkins DS, Patiño-Garcia A, Lupo PJ, Scheurer ME, Morton L, Armstrong GT, Sapkota Y, Gramatges MM, Serra M, Hattinger C, Scotl… J Natl Cancer Inst 2025 PLCO
Physical activity and molecular subtypes of colorectal cancer: a pooled observational analysis and Mendelian randomization study. 41031512 Chalitsios CV, Markozannes G, Aglago EK, Berndt SI, Buchanan DD, Campbell PT, Cao Y, Chan AT, Dimou N, Drew DA, French AJ, Georgeson P, Giannakis M, Gruber SB, Gunter MJ, Harrison TA, Hoffmeister M, Hsu L, Huang WY, Hullar MAJ, Huyghe JR, Lynch BM, … JNCI Cancer Spectr 2025 PLCO
Association of Genetic Liability to Allergic Diseases with Overall and Early-Onset Colorectal Cancer Risk: A Mendelian Randomization Study. 39982694 Alduhayh S, Laskar RS, Jiang X, Zhu Z, Vincent EE, Constantinescu AE, Buchanan DD, Grant RC, Phipps AI, Brenner H, Huang WY, Kweon SS, Li L, Pearlman R, Castellví-Bel S, Gruber SB, Li CI, Pellatt A, Platz EA, Van Guelpen B, Zheng W, Chan AT, Figueir… Cancer Epidemiol Biomarkers Prev 2025 PLCO
Waist Circumference, a Body Shape Index, and Molecular Subtypes of Colorectal Cancer: A Pooled Analysis of Four Cohort Studies. 39898780 Chalitsios CV, Markozannes G, Papagiannopoulos C, Aglago EK, Berndt SI, Buchanan DD, Campbell PT, Cao Y, Chan AT, Dimou N, Drew DA, French AJ, Georgeson P, Giannakis M, Gruber SB, Gunter MJ, Harrison TA, Hoffmeister M, Hsu L, Huang WY, Hullar MAJ, H… Cancer Epidemiol Biomarkers Prev 2025 PLCO
Integrating Pathogenic Variants, Polygenic Risk Score, and Family History for Prostate Cancer Risk Estimation in Men of African Ancestry. 41219045 Chen F, Sheng X, Wang A, Xu Y, Hughley R, Xiong W, Pooler L, Wan P, Gundell SM, Kigozi G, Nakigozi G, Nalugoda F, Kagaayi J, Kigozi GN, Mugamba S, Kyasanku E, Nkale J, Olwa VO, Lubwama A, Daama A, Nakajugo R, Adusei B, Jalloh M, Gueye SM, Adjei AA, … Eur Urol 2025 PLCO
Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33. 40307206 Connelly KE, Hullin K, Abdolalizadeh E, Zhong J, Eiser D, O'Brien A, Collins I, Das S, Duncan G, Pancreatic Cancer Cohort Consortium, Pancreatic Cancer Case-Control Consortium, Chanock SJ, Stolzenberg-Solomon RZ, Klein AP, Wolpin BM, Hoskins JW, And… Nat Commun 2025 PLCO
Threshold-Based Overlap of Breast Cancer High-Risk Classification Using Family History, Polygenic Risk Scores, and Traditional Risk Models in 180,398 Women. 41228354 Ho PJ, Loo CKY, Lim RJY, Goh MH, Abubakar M, Ahearn TU, Andrulis IL, Antonenkova NN, Aronson KJ, Augustinsson A, Behrens S, Bodelon C, Bogdanova NV, Bolla MK, Brantley KD, Brenner H, Byers H, Camp NJ, Castelao JE, Cessna MH, Chang-Claude J, Chanock … Cancers (Basel) 2025 PLCO
Genetic and Cellular Architecture of Breast Cancer Risk in Multi-Ancestry Studies of 159,297 Cases and 212,102 Controls. 40909829 Li JL, Zanti M, Williams J, Jahagirdar O, Jia G, Turcan A, Hu Q, Brandenburg JT, Yan L, Ho WK, Li J, Miranda JP, Godbole D, Dias JA, Zhang X, Dorling L, Chen WC, Boddicker N, Wang Y, Martin A, Zhang YD, Dennis J, John EM, Torres-Mejia G, Kushi L, We… medRxiv 2025 PLCO
Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification. 40413188 Zanti M, O'Mahony DG, Parsons MT, Dorling L, Dennis J, Boddicker NJ, Chen W, Hu C, Naven M, Yiangou K, Ahearn TU, Ambrosone CB, Andrulis IL, Antoniou AC, Auer PL, Baynes C, Bodelon C, Bogdanova NV, Bojesen SE, Bolla MK, Brantley KD, Camp NJ, Campbel… Nat Commun 2025 PLCO
Refining breast cancer genetic risk and biology through multi-ancestry fine-mapping analyses of 192 risk regions. 39753771 Jia G, Chen Z, Ping J, Cai Q, Tao R, Li C, Bauer JA, Xie Y, Ambs S, Barnard ME, Chen Y, Choi JY, Gao YT, Garcia-Closas M, Gu J, Hu JJ, Iwasaki M, John EM, Kweon SS, Li CI, Matsuda K, Matsuo K, Nathanson KL, Nemesure B, Olopade OI, Pal T, Park SK, Pa… Nat Genet 2025 PLCO
Higher insoluble fiber intake is associated with a lower risk of prostate cancer: results from the PLCO cohort. 38243202 Shen Y, Yuan Q, Shi M, Luo B BMC Public Health 2024 PLCO
Prediction of prognosis and treatment response in ovarian cancer patients from histopathology images using graph deep learning: a multicenter retrospective study. 38241820 Yang Z, Zhang Y, Zhuo L, Sun K, Meng F, Zhou M, Sun J Eur J Cancer 2024 PLCO
Contributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer. 38175578 León-Letelier RA, Dou R, Vykoukal J, Yip-Schneider MT, Maitra A, Irajizad E, Wu R, Dennison JB, Do KA, Zhang J, Schmidt CM, Hanash S, Fahrmann JF Clin Chem 2024 PLCO
Helicobacter hepaticus and Helicobacter bilis in liver and biliary cancers from ATBC and PLCO. 38332674 Murphy G , Freedman ND , Abnet CC , Albanes D , Cross AJ , Huang WY , Koshiol J , McGlynn K , Parisi D , Männistö S , Weinstein SJ , Waterboer T , Butt J Helicobacter 2024 PLCO
Associations of serum trimethylamine N-oxide and its precursors with colorectal cancer risk in the Prostate, Lung, Colorectal, Ovarian Cancer Screening Trial Cohort. 38285606 Byrd DA , Zouiouich S , Karwa S , Li XS , Wang Z , Sampson JN , Loftfield E , Huang WY , Hazen SL , Sinha R Cancer 2024 PLCO
Polymorphisms in transcription factor binding sites and enhancer regions and pancreatic ductal adenocarcinoma risk. 38308339 Ünal P, Lu Y, Bueno-de-Mesquita B, van Eijck CHJ, Talar-Wojnarowska R, Szentesi A, Gazouli M, Kreivenaite E, Tavano F, Małecka-Wojciesko E, Erőss B, Oliverius M, Bunduc S, Nóbrega Aoki M, Vodickova L, Boggi U, Giaccherini M, Kondrackiene J, Chammas … Hum Genomics 2024 PLCO
Evidence for a causal link between intra-pancreatic fat deposition and pancreatic cancer: A prospective cohort and Mendelian randomization study. 38280379 Yamazaki H, Streicher SA, Wu L, Fukuhara S, Wagner R, Heni M, Grossman SR, Lenz HJ, Setiawan VW, Le Marchand L, Huang BZ Cell Rep Med 2024 PLCO