The Lung Screening Study (LSS) was a pilot study designed to assess the feasibility of conducting a large scale randomized controlled trial (RCT) of low radiation dose spiral computed tomography (LDCT) versus chest X-ray (CXR) for lung cancer screening. During the fall of 2000, six PLCO screening centers recruited a total of 3,318 heavy or long-term smokers who were not participants in the PLCO trial and randomized them to receive either a screening LDCT scan (1,660 participants) or screening posteroanterior view chest radiograph (CXR) [1,658 participants].

The results of the LSS demonstrated convincingly the feasibility of an RCT of LDCT scanning in the United States.

This website is organized into several sections as follows.

• Learn About
  This describes the trial, explaining how and what data were collected. The main findings of the trial can be found here.
• Datasets
  This page has detailed documentation of the datasets available on this website, including data dictionaries.
• Approved Projects
  Search through approved projects that used this trial's data.
• Publications
  Search through published articles on this trial's data.
• Begin a new Project
  Learn how to access the available datasets.
  Overview:
  1. Submit a project proposal.
  2. Brief review by NCI.
  3. Complete a Data Transfer Agreement.
  4. Receive access to datasets.
• Contact Us
  If you have any questions about the data or access to it, please contact us.