Diet-omics and the Risks of Cancers
Principal Investigator
Name
Kanran Wang
Degrees
M.D., Ph.D.
Institution
Chongqing University Cancer Hospital
Position Title
research fellow, attending doctor
Email
About this CDAS Project
Study
PLCO
(Learn more about this study)
Project ID
PLCO-1835
Initial CDAS Request Approval
Mar 5, 2025
Title
Diet-omics and the Risks of Cancers
Summary
Cancer remains the most commonly mortality reason. Therefore, identifying modifiable risk factors for cancer is essential to formulate precision public health interventions that enhance survival outcomes and mitigate the global disease burden. A growing body of evidence indicates that modifiable dietary patterns may also significantly influence cancer risk. We submit this formal request to access data from the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial database for a research project investigating the Association between Diet-Omic Profiles and Major Cancer Types. We want to explore the effects of different food types and frequencies on various types of cancer.
Aims
1.To explore the interplay between dietary patterns (macro/micronutrient intake, food frequency, etc) across cancers.
2.To identify potential biomarkers linking dietary factors to cancer risk and progression using machine learning and multivariate regression models.
Collaborators
Kang Wang MD,PhD Karolinska Institute
Yongzhong Wu MD, PhD Chongqing University Cancer Hospital
Wei Zhou MD, PhD Chongqing University Cancer Hospital