BMI trajectories and colorectal cancer carcinogenesis.
Principal Investigator
Name
Zhuyue Li
Degrees
Ph.D.
Institution
Sichuan Cancer Hospital and Institute
Position Title
Dr.
Email
About this CDAS Project
Study
PLCO
(Learn more about this study)
Project ID
PLCO-1671
Initial CDAS Request Approval
Sep 26, 2024
Title
BMI trajectories and colorectal cancer carcinogenesis.
Summary
More and more researches have revealed that body mass index (BMI) has an important effect on colorectal cancer risk, however, the impact of BMI trajectories on colorectal cancer risk remains uncharted territory. Especially the impact on colorectal cancer carcinogenesis. It is vital to evaluate the effect of BMI trajectory on different colorectal cancer stages using appropriate epidemiology methods. Our objective is to investigate the relationship between BMI trajectories and the risk of colorectal cancer carcinogenesis within a cohort from the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial. We endeavor to uncover distinct patterns of BMI trajectory effects on various subpopulations.
Aims
1. To explore the correlation between BMI trajectories and colorectal cancer carcinogenesis.
2. To unveil unique patterns of BMI trajectory effects within diverse subpopulations.
Collaborators
Qing Yang, Sichuan Cancer Hospital and Institute, Chengdu, Sichuan, P. R. China
Kaihan Yang, Chengdu University, Chengdu, Sichuan, P.R.China