Association between adherence to the Eat-Lancet Diet and lung cancer incidence and mortality in the US population: A prospective cohort study
Principal Investigator
Name
Linglong Peng
Degrees
Ph.D.
Institution
The Second Affiliated Hospital of Chongqing Medical University
Position Title
Dr.
Email
About this CDAS Project
Study
PLCO
(Learn more about this study)
Project ID
PLCO-1177
Initial CDAS Request Approval
Mar 16, 2023
Title
Association between adherence to the Eat-Lancet Diet and lung cancer incidence and mortality in the US population: A prospective cohort study
Summary
Lung cancer, the most common cancer worldwide, accounts for 11.6% of all cancer cases and represents the leading cause of cancer-related deaths, with over 1.7 million fatalities worldwide in 2018(1). In recent years, growing attention has been accorded to the role of dietary quality in mitigating cancer risks and curbing mortality rates(2, 3). Nevertheless, conventional healthy dietary patterns have overlooked the significance of sustainability(4). In 2019, the EAT-Lancet Commission on Healthy Eating from Sustainable Food Systems recommended the Eat-Lancet Diet (ELD) as a reference diet for promoting environmental sustainability and reducing diet-related chronic diseases and mortality(4). The ELD primarily consists of plant-based foods, limited dairy products, and a small amount of meat(4). However, few previous studies have focused on examining the ELD's association with cancer incidence and mortality, especially lung cancer(5, 6). Consequently, we utilized prospective data derived from PLCO Screening Trial to investigate the potential relationship between adherence to the ELD and reduced lung cancer incidence and mortality in the United States population.
1.The L. Lung cancer: some progress, but still a lot more to do. Lancet,(2019) 394: 1880. doi: 10.1016/S0140-6736(19)32795-3.
2.Mentella MC, Scaldaferri F, Ricci C, Gasbarrini A and Miggiano GAD. Cancer and Mediterranean Diet: A Review. Nutrients,(2019) 11. doi: 10.3390/nu11092059.
3.Park SY, Boushey CJ, Shvetsov YB, Wirth MD, Shivappa N, Hebert JR, et al. Diet Quality and Risk of Lung Cancer in the Multiethnic Cohort Study. Nutrients,(2021) 13. doi: 10.3390/nu13051614.
4.Willett W, Rockstrom J, Loken B, Springmann M, Lang T, Vermeulen S, et al. Food in the Anthropocene: the EAT-Lancet Commission on healthy diets from sustainable food systems. Lancet,(2019) 393: 447-492. doi: 10.1016/S0140-6736(18)31788-4.
5.Zhang S, Dukuzimana J, Stubbendorff A, Ericson U, Borne Y and Sonestedt E. Adherence to the EAT-Lancet diet and risk of coronary events in the Malmo Diet and Cancer cohort study. Am J Clin Nutr,(2023. doi: 10.1016/j.ajcnut.2023.02.018.
6.Stubbendorff A, Sonestedt E, Ramne S, Drake I, Hallstrom E and Ericson U. Development of an EAT-Lancet index and its relation to mortality in a Swedish population. Am J Clin Nutr,(2022) 115: 705-716. doi: 10.1093/ajcn/nqab369.
1.The L. Lung cancer: some progress, but still a lot more to do. Lancet,(2019) 394: 1880. doi: 10.1016/S0140-6736(19)32795-3.
2.Mentella MC, Scaldaferri F, Ricci C, Gasbarrini A and Miggiano GAD. Cancer and Mediterranean Diet: A Review. Nutrients,(2019) 11. doi: 10.3390/nu11092059.
3.Park SY, Boushey CJ, Shvetsov YB, Wirth MD, Shivappa N, Hebert JR, et al. Diet Quality and Risk of Lung Cancer in the Multiethnic Cohort Study. Nutrients,(2021) 13. doi: 10.3390/nu13051614.
4.Willett W, Rockstrom J, Loken B, Springmann M, Lang T, Vermeulen S, et al. Food in the Anthropocene: the EAT-Lancet Commission on healthy diets from sustainable food systems. Lancet,(2019) 393: 447-492. doi: 10.1016/S0140-6736(18)31788-4.
5.Zhang S, Dukuzimana J, Stubbendorff A, Ericson U, Borne Y and Sonestedt E. Adherence to the EAT-Lancet diet and risk of coronary events in the Malmo Diet and Cancer cohort study. Am J Clin Nutr,(2023. doi: 10.1016/j.ajcnut.2023.02.018.
6.Stubbendorff A, Sonestedt E, Ramne S, Drake I, Hallstrom E and Ericson U. Development of an EAT-Lancet index and its relation to mortality in a Swedish population. Am J Clin Nutr,(2022) 115: 705-716. doi: 10.1093/ajcn/nqab369.
Aims
Our objective is to examine whether following the Eat-Lancet Diet is linked to a reduced incidence and mortality of lung cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
Collaborators
Yi Xiao, Haitao Gu, Yaxu Wang, Linglong Peng (Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. )
Ling Xiang (Department of Clinical Nutrition, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.)
Related Publications
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Association between adherence to Eat-Lancet diet and incidence and mortality of lung cancer: A prospective cohort study.
Xiao Y, Peng L, Xu Z, Tang Y, He H, Gu H, Wang Y, Xiang L
Cancer Sci. 2023 Aug 31 PUBMED