Type 2 diabetes prevention diet and the risk of pancreatic cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
Principal Investigator
Name
Chen-Yang Wang
Degrees
Ph.D.
Institution
The Frist Affiliated Hospital of Chongqing Medical University
Position Title
Dr.
Email
About this CDAS Project
Study
PLCO
(Learn more about this study)
Project ID
PLCO-969
Initial CDAS Request Approval
Apr 25, 2022
Title
Type 2 diabetes prevention diet and the risk of pancreatic cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
Summary
Type 2 diabetes (T2D) is a serious threat to human health and is a predisposing factor for many chronic diseases including cardiovascular disease and cancer [1]. A dietary diabetes risk reduction score was developed for T2D prevention, which features high intakes of cereal fiber, polyunsaturated fats, nuts, and coffee; and low amounts of carbohydrates, trans fat, sweets, and red and processed meat [2]. Previous study has reported that greater adherence to the T2D prevention diet was associated with a lower risk of developing Hepatocellular carcinoma among US men and women [3]. However, there are no epidemiological studies evaluating the potential association between T2D prevention diet and pancreatic cancer risk.
[1] Parvin M, Zahra B, Asghar G, et al. Type 2 Diabetes and Cancer: An Overview of Epidemiological Evidence and Potential Mechanisms. Crit Rev Oncog. 2019;24(3):223-233.
[2] Rhee JJ, Mattei J, Hughes MD, et al. Dietary diabetes risk reduction score, race and ethnicity, and risk of type 2 diabetes in women. Diabetes Care. 2015;38:596–603.
[3] Luo X, Sui J, Yang W, et al. Type 2 Diabetes Prevention Diet and Hepatocellular Carcinoma Risk in US Men and Women. Am J Gastroenterol. 2019;114(12):1870-1877.
[1] Parvin M, Zahra B, Asghar G, et al. Type 2 Diabetes and Cancer: An Overview of Epidemiological Evidence and Potential Mechanisms. Crit Rev Oncog. 2019;24(3):223-233.
[2] Rhee JJ, Mattei J, Hughes MD, et al. Dietary diabetes risk reduction score, race and ethnicity, and risk of type 2 diabetes in women. Diabetes Care. 2015;38:596–603.
[3] Luo X, Sui J, Yang W, et al. Type 2 Diabetes Prevention Diet and Hepatocellular Carcinoma Risk in US Men and Women. Am J Gastroenterol. 2019;114(12):1870-1877.
Aims
To investigate the association of T2D prevention diet with pancreatic cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
Collaborators
no