Vitamin K intake and breast, endometrial, ovarian and colorectal cancer incidence and mortality in the Prostate, Lung, Colorectal, and Ovarian Cancer (PLCO) Screening Trial
Principal Investigator
Name
Kang Wang
Degrees
M.D
Institution
The First Affiliated hospital of Chongqing Medical university
Position Title
MD
Email
About this CDAS Project
Study
PLCO
(Learn more about this study)
Project ID
PLCO-566
Initial CDAS Request Approval
Jan 8, 2020
Title
Vitamin K intake and breast, endometrial, ovarian and colorectal cancer incidence and mortality in the Prostate, Lung, Colorectal, and Ovarian Cancer (PLCO) Screening Trial
Summary
It was reported that vitamin K inhibited the growth and invasion of solid cancer cells, and an altered expression of vitamin K-dependent proteins in breast cancer has been linked to their survival and response to chemotherapy. However, little is known about the effect of vitamin K intake on breast cancer in human populations.
Aims
We evaluated the associations of dietary intake of phylloquinone (vitamin K-1), menaquinones (vitamin K-2), and total vitamin K with the development of prostate cancer among participants in the Prostate, Lung, Colorectal, and Ovarian Cancer
(PLCO) Screening Trial.
Collaborators
Zhuyue Li